Cleo | Perimenopause Support
Finally, support for the symptoms no one warned you about.
Clinically dosed. Hormone-free. Every milligram on the label.
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Description
Cleo is a daily perimenopause formula built for the symptoms most supplements ignore — the 2am wake-ups, the racing heart, the sudden panic that comes out of nowhere.
Six clinically studied ingredients, every dose printed on the label. No hormones, no proprietary blends, no titanium dioxide. Two capsules a day.
The Results
Cleo works gradually as the ingredients build up in your system. Here's what women typically report:
- Weeks 1–2: Sleep starts to feel deeper. Small shifts, nothing dramatic.
- Weeks 3–4: Fewer night wake-ups. Calmer mornings.
- Weeks 5–8: The bigger changes — steadier mood, more energy, feeling like yourself again.
Give it a full 60 days. That's why our guarantee runs that long.
Ingredients
- KSM-66® Ashwagandha — 300 mg
- Black Cohosh Root Extract — 40 mg
- Chasteberry (Vitex) — 40 mg
- Chromium Picolinate — 600 mcg
- Vitamin B6 — 2 mg
- Vitamin D3 — 15 mcg
Other ingredients: rice flour, vegetarian capsule (cellulose). Vegan, non-GMO, gluten-free, hormone-free.
Shipping & Returns
Orders placed before 2pm ET ship the same business day from our US facility. Standard delivery is 3–5 business days. Free shipping on every subscription order.
Not feeling a difference within 60 days? Email us for a full refund — no questions, and nothing to send back.
The Science
Three symptoms. One trigger.
What's happening
Your brain misreads the temperature
Swinging estrogen throws off the hypothalamus — the part of your brain that reads body heat. Half a degree now registers as overheating, so it fires a full cooling response and you wake up soaked.
Black Cohosh · 40mg
Works on that thermostat directly. Recognized in Germany specifically for night sweats.*
What's happening
Adrenaline floods in behind it
The same misfire releases a surge of cortisol and adrenaline. Your heart hits 130 while you're lying perfectly still — and without estrogen buffering it, that surge lasts far longer than it should.
KSM-66® Ashwagandha · 300mg
The most studied ashwagandha extract there is. Helps your body regulate cortisol.*
What's happening
Your brain calls it danger
It was asleep. It gets hit with adrenaline, scans for a threat, finds nothing — and panics anyway. Falling progesterone is what took the calm that normally holds this back.
Chasteberry · 40mg
Used in European gynecology for decades to support progesterone balance.*
Clinically Dosed.Honestly Labeled.*
When real research meets a formula built for the phase no one warns you about.
4 Clinically-Studied Ingredients Doing Different Jobs
KSM-66® Ashwagandha
300mg per serving of the world's most clinically studied ashwagandha extract, backed by 24+ human trials. Helps the body regulate cortisol — the hormone behind those 2am adrenaline surges.
Black Cohosh
40mg of standardized root extract from Actaea racemosa. Recognized in Germany specifically for night sweats, nervousness and heart palpitations during hormonal transition.
Chasteberry (Vitex)
40mg per serving of a berry used in European gynecology for decades. Supports progesterone balance — the hormone that drops first and hardest in perimenopause.
Vitamin D3
Bone density drops fastest in the years around menopause. D3 supports calcium absorption, immune function and mood regulation when your body needs it most.
Real Stories, Real Answers
What women in perimenopause are saying about Cleo
"I finally sleep through the night."
I was waking at 2am drenched, heart pounding, every single night for almost a year. Three weeks in and it just... stopped. I'm on month four now and I honestly feel like myself again.
"My doctor said anxiety. It was perimenopause."
Two ER visits for heart palpitations. Normal EKG both times, and a prescription I never filled. Nobody said the word perimenopause once. Cleo gave me an explanation and my nights back.
"Subtle at first, then everything changed."
Week one I felt nothing and almost quit. Week three I realized I hadn't changed my shirt in the middle of the night in eleven days. Four ingredients, no mystery blend. That's why I trust it.
Feel Like Yourself. Every Day.
From calmer nights to steadier mornings, here's what Cleo supports every single day.
Cooler, Drier
Nights
A Calmer
Heart Rhythm
Deeper, Unbroken
Sleep
Steadier Mood
& Clarity
What to expect
This isn't a 30-day fix. It's a routine.
Perimenopause lasts four to eight years on average. Cleo isn't here to end it — it's here to make it livable, one night at a time. Here's how it usually unfolds.
- Honestly? Most women feel very little
- Maybe one or two slightly deeper nights
- This is the part where people quit. Don't
- Fewer nights waking up drenched
- Your heart stays quieter at 2am
- Mornings stop feeling like a fight
- Sleep holds through the night more often
- The panic loses its grip
- You stop bracing for the next bad night
- Steady nights become the normal, not the exception
- Support that keeps working as long as you need it
- Two capsules, every morning, for as long as this phase lasts
Here's what you've probably been offered
Three answers most women get. None of them touch what's actually happening.
"It's just stress."
Bloodwork normal, EKG normal, sent home. 39% of women never hear the word perimenopause from a doctor.
"Try this prescription."
Something for the panic, nothing for the hormone shift underneath it. The cause keeps running.
"Just wait it out."
Four to eight years on average. That's a lot of nights to give away and hope it passes.
Cleo goes after the trigger, not the symptom
Four clinically studied ingredients aimed at the hormonal cascade that starts every one of those 2am episodes.
- Hormone-free formula
- Every dose on the label
- Two capsules a day
- No prescription needed
60-day money back guarantee · Cancel anytime
The comparison
Not every menopause supplement is built the same
Most were made for menopause. Cleo was made for the years before it.
60-day money back guarantee · Free shipping on subscriptions
Feel the difference
60-Day Risk-Free Trial
Give Cleo two full months. If your nights haven't changed, email us and we'll refund you completely — no questions, no phone calls, and nothing to send back.
The Moment It Finally Made Sense
"I had no idea the two were connected."
I'd been treating the palpitations and the sweating like two separate problems for a year. Reading that they come from the same misfire was the first time any of it made sense. Started Cleo the same week and by month two both had eased off together.
"I was 44 and convinced something was seriously wrong."
Nobody had said the word perimenopause to me. I thought 44 was way too young. Learning that estrogen starts swinging years before anything else changes explained everything I'd been through. The relief of just knowing was almost as big as the relief from the symptoms.
"The panic wasn't in my head after all."
I'd started believing I was becoming an anxious person. It never occurred to me that a hormone dropping could take my calm with it. That reframe alone was worth it — and the nights got quieter too.
"I looked up every ingredient before I ordered."
I'm skeptical of supplements. The fact that every dose is printed and I could actually verify the studies behind them is why I tried this one. Nothing hidden behind a proprietary blend.
"I sent it to my sister the next day."
She's 41 and had been telling me for months that something felt off but her labs were fine. I forwarded her the page about what happens to the hypothalamus. She cried reading it. We both take it now.
"Month five and I'm still taking it."
I understood early on this isn't something you finish. I'm somewhere in the middle of a phase that lasts years, so it just became part of my morning like coffee. No decision to make each month.